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Rebel-held areas of Aleppo were hit by about 30 strikes overnight

according to the Syrian Observatory for Human Rights, after the Syrian army announced it was launching a new offensive to retake the entire city. Video provided by AFP Newslook

Russian aircraft dropped dozens of bombs Friday on rebel and Islamic State areas, including civil defense centers, a human rights group said, as the Syrian government announced a major military operation in the city. The latest violence appears to doom a cease-fire that has been violated repeatedly since it went into effect Sept 12.

Russian aircraft dropped 50 bombs in the city and 30 in the surrounding areas, killing at least 14 civilians, according to the Syrian Observatory for Human Rights, a London-based monitoring group with activists on the ground. Residents told Reuters the attacks included helicopters dropping bombs made from oil drums, a common tactic of the Syrian President Bashar Assad's army during the country's 5-year-old civil war.

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Foreign affairs reporter Oren Dorell explains who is fighting whom in the five-year Syrian Civil War in two minutes. USA TODAY

The Syrian military command in the city announced the start of its operations in the eastern neighborhoods of the city, and called "on citizens to keep away from sites and centers of armed terrorist groups," according to the government-run Syrian Arab News Agency, SANA. The military is offering to provide civilians shelter, "including those who were misled" by rebel fighters, the statement said.

Doctors Without Borders said in a statement that 145 people were admitted in the past two days to eight hospitals it runs in Aleppo, and that residents who've been denied food and medical aid for months are now targets of "indiscriminate bombing of civilian areas."

“People in Aleppo already suffocating under the effects of the siege, have yet again come under horrific attack”, said Carlos Francisco, the aid group's head of mission in Syria. “No aid, including urgent medical supplies is allowed to enter."

Ibrahim Alhaj, a member of the Syrian Civil Defense, told the Associated Press that three of the group's four centers in the city were targeted in the air strikes. Secretary of State John Kerry praised the humanitarian group, also known as the White Helmets, at the United Nations General Assembly in New York City on Thursday.

When bombs explode in #Syria, the White Helmets are the brave 1st responders on the scene. Honored to meet their leader & #Aleppo activists.

— John Kerry (@JohnKerry) September 23, 2016

Battles raged across many fronts of Aleppo, 11 days after a U.S.-Russian cease-fire agreement was supposed to allow humanitarian supplies to reach the same areas now under attack. The agreement, which called for seven days of calm and humanitarian access, was supposed to lead to a U.S.-Russian effort to share intelligence and targeting information on terrorist groups Islamic State and Nusra Front, al-Qaeda's franchise in Syria.

Kerry, who learned of the military offensive during a meeting on Syria in New York City on Thursday night, said it “is exactly the kind of regime action that has done so much damage" to the cease-fire.

Russia and Assad “must do their part, or (the cease-fire) will have no chance,” he said. “The question now is whether there remains any real chance of moving forward, because it’s clear we cannot continue on the same path any longer.”

The cease-fire has been collapsing after Russia charged that a U.S.-led coalition bombed Syrian forces on Sept. 17, killing dozens of troops in what Kerry apologetically called a "terrible accident." Then on Monday, the U.S. charged that Russia was responsible for a strike on a U.N. aid convoy in Aleppo. Russia denied responsibility. At the same time, the Syrian military said it would no longer abide by the cease-fire because of violations by rebel groups.

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THE SYRIAN CIVIL WARRaw: Aid convoy hit by airstrike near Aleppo | 0:57

Syria's cease-fire has faltered further after an aid convoy was hit by airstrikes, with activists saying a number of people were killed in the attack, mostly truck drivers and Red Crescent workers. (Sept. 20) AP

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THE SYRIAN CIVIL WARAirstrikes hit aid Convoy in Syria | 0:51

Airstrikes hit a U.N. Humanitarian convoy in Syria on Monday. At least 12 people are reported dead, mostly humanitarian aid workers. It is unclear who launched the attack, although Russian and Syrian aircraft are known to operate in the area. (Sept. 20) AP

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THE SYRIAN CIVIL WARGoogle to help George and Amal Clooney educate Syrian refugee children in Lebanon | 0:39

George and Amal Clooney are launching an ambitious initiative to educate Syrian refugee children in Lebanon - and they are getting started with a big injection of cash and brain power from Google. USA TODAY

3 of 22
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THE SYRIAN CIVIL WARKerry: Syria Truce 'Holding but Fragile' | 0:23

Calling the Syrian ceasefire "fragile," Secretary of State John Kerry says humanitarian aid trucks are moving to some beseiged cities. (Sept. 19) AP

4 of 22
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THE SYRIAN CIVIL WARSyrian ceasefire on brink of collapse | 0:38

For the first time in nearly a week, strikes hit rebel-held areas of Aleppo following a U.S.-led raid that killed scores of Syrian regime soldiers. The US has said it believed it was striking Islamic State group fighters. Video provided by AFP Newslook

5 of 22
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THE SYRIAN CIVIL WARSoldiers replace tourists in Aleppo's battered old city | 2:29

Instead of colourful, handmade caps for sale to Syrians and foreign tourists, Zakaria Mosuli -- the last tailor in Aleppo's battered Old City -- now sews military headwear almost exclusively for soldiers. Video provided by AFP Newslook

6 of 22
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THE SYRIAN CIVIL WARRaw: UN Cars Enter Syria, Aid Stuck At Border | 1:00

Cars emblazoned with the logo of the United Nations were seen crossing from Turkey into Syria via the Cilvegozu border gate on Saturday. UN aid trucks have been stuck in the customs area for several days, waiting to deliver aid in Syria. (Sept. 17) AP

7 of 22
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THE SYRIAN CIVIL WARUN urges Syria regime to allow aid deliveries | 1:07

The UN Syria envoy urges the Damascus government to allow humanitarian aid deliveries indicating the regime has broken its pledges on the distribution of life-saving supplies. Video provided by AFP Newslook

8 of 22
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THE SYRIAN CIVIL WARWhat is happening in the Syrian Civil War | 2:15

Foreign affairs reporter Oren Dorell explains who is fighting whom in the five-year Syrian Civil War in two minutes. USA TODAY

9 of 22
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THE SYRIAN CIVIL WARUS-Russia plan 'may be last chance to save Syria, says Kerry | 1:01

US Secretary of State John Kerry urges Syria's warring parties to observe a US-Russian brokered ceasefire and warned it could be a last chance to save the country. Video provided by AFP Newslook

10 of 22
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THE SYRIAN CIVIL WARAnother cease-fire begins in Syria | 1:33

The cease-fire began Monday at sundown, and Secretary of State John Kerry is cautiously optimistic. Video provided by Newsy Newslook

11 of 22
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THE SYRIAN CIVIL WARSyria truce: Calm has returned to rebel-held parts of Aleppo | 0:37

In Aleppo's rebel-held neighbourhoods, residents experience a rare day of calm following the implementation of a ceasefire billed as the "last chance" for peace in Syria. Video provided by AFP Newslook

12 of 22
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THE SYRIAN CIVIL WARDozens treated for breathing problems after Syria attack | 0:45

Dozens of people had to be treated for breathing problems in the Syrian battlefront city of Aleppo after regime helicopters dropped barrel bombs on a rebel-held district, a monitor said. Video provided by AFP Newslook

13 of 22
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THE SYRIAN CIVIL WARKerry: 'Syria Breakthrough not Built on Trust' | 1:47

Secretary of State, John Kerry spelled out his views about the ceasefire agreement that has been negotiated to bring a stop to the fighting in Syria. Kerry said, "no one is building this based on trust." (Sept. 10) AP

14 of 22
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THE SYRIAN CIVIL WARRaw: Syrian Military Launches Aleppo Offensive | 1:04

Syrian pro-government forces backed by airstrikes launched a wide offensive in the northern city of Aleppo on Sunday, capturing areas they lost last month and almost besieging rebel-held neighborhoods, state media and opposition activists said. (Sept. 4) AP

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THE SYRIAN CIVIL WARISIS: top-tier leader Abu Mohammed al-Adnani killed in Aleppo | 0:27

Islamic State spokesman Abu Muhammad al-Adnani, one of the jihadist group’s longest-serving officials, has been killed in Aleppo in Syria, its Amaq News Agency reported on Tuesday. WIBBITZ

16 of 22
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THE SYRIAN CIVIL WARRaw: Explosions in Syria Kills Dozens | 0:54

Syrian state media reports that several bombings in government-controlled territory have killed more than three dozen people. Islamic State militants claimed responsibility for at least one of the bombings. (Sept. 5) AP

17 of 22
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THE SYRIAN CIVIL WARNo humanitarian convoys in Syria in a month | 1:12

Aid convoys have not reached Syria's besieged areas with desperately needed food and medicine for the past month, the UN envoy to the war-ravaged country, Staffan de Mistura, says. Video provided by AFP Newslook

18 of 22
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THE SYRIAN CIVIL WARRaw: Turkish forces launch offensive in Syria | 1:09

Turkey's state-run Anadolu Agency said on Wednesday that Turkish tanks have crossed into Syria as part of a military operation to free a border town held by the Islamic State group. (Aug. 24) AP

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THE SYRIAN CIVIL WARRaw: Fighting intensifies around Aleppo | 1:17

Fighting intensified around Aleppo on Wednesday as Syrian government forces used rocket propelled grenades and tanks to try and dislodge the opposition. (Aug. 3) AP

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THE SYRIAN CIVIL WARWounded Syrian child sparks social media outrage | 0:39

The Aleppo Media Center published a video showing a child that it said had been rescued after strikes on a area in rebel-held eastern Aleppo. The images of the child covered in dust and blood in the ambulance have brought the spotlight on the plight of civilians in Syria's conflict-hit second city. Video provided by AFP Newslook

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THE SYRIAN CIVIL WARAt least 11 killed in airstrikes west of Aleppo | 0:35

At least 11 people, including five children, are killed in air strikes on the rebel-held town of Atareb west of Aleppo, according to the Syrian Observatory for Human Rights. Video provided by AFP Newslook

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    Raw: Aid convoy hit by airstrike near Aleppo
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    Airstrikes hit aid Convoy in Syria
  • Google to help George and Amal Clooney educate Syrian refugee children in Lebanon
    Google to help George and Amal Clooney educate Syrian refugee children in Lebanon
  • Kerry: Syria Truce 'Holding but Fragile'
    Kerry: Syria Truce 'Holding but Fragile'
  • Syrian ceasefire on brink of collapse
    Syrian ceasefire on brink of collapse
  • Soldiers replace tourists in Aleppo's battered old city
    Soldiers replace tourists in Aleppo's battered old city
  • Raw: UN Cars Enter Syria, Aid Stuck At Border
    Raw: UN Cars Enter Syria, Aid Stuck At Border
  • UN urges Syria regime to allow aid deliveries
    UN urges Syria regime to allow aid deliveries
  • What is happening in the Syrian Civil War
    What is happening in the Syrian Civil War
  • US-Russia plan 'may be last chance to save Syria, says Kerry
    US-Russia plan 'may be last chance to save Syria, says Kerry
  • Another cease-fire begins in Syria
    Another cease-fire begins in Syria
  • Syria truce: Calm has returned to rebel-held parts of Aleppo
    Syria truce: Calm has returned to rebel-held parts of Aleppo
  • Dozens treated for breathing problems after Syria attack
    Dozens treated for breathing problems after Syria attack
  • Kerry: 'Syria Breakthrough not Built on Trust'
    Kerry: 'Syria Breakthrough not Built on Trust'
  • Raw: Syrian Military Launches Aleppo Offensive
    Raw: Syrian Military Launches Aleppo Offensive
  • ISIS: top-tier leader Abu Mohammed al-Adnani killed in Aleppo
    ISIS: top-tier leader Abu Mohammed al-Adnani killed in Aleppo
  • Raw: Explosions in Syria Kills Dozens
    Raw: Explosions in Syria Kills Dozens
  • No humanitarian convoys in Syria in a month
    No humanitarian convoys in Syria in a month
  • Raw: Turkish forces launch offensive in Syria
    Raw: Turkish forces launch offensive in Syria
  • Raw: Fighting intensifies around Aleppo
    Raw: Fighting intensifies around Aleppo
  • Wounded Syrian child sparks social media outrage
    Wounded Syrian child sparks social media outrage
  • At least 11 killed in airstrikes west of Aleppo
    At least 11 killed in airstrikes west of Aleppo
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